The June 2015 cover of Structure is an illustration by Melissa Thomas-Baum and Hstau Y. Liao. It accompanies this article published in the same issue: Liao, H.Y., Hashem, Y., and Frank, J. (2015). Efficient estimation of three-dimensional covariance and its application in the analysis of heterogeneous samples in cryo-electron microscopy. Structure 23, 1129–1137.
The journal has launched a new blog named “Biology in 3D” to open it up to more people and teach them about the importance of structural biology. In their latest post, senior editor, Milka Kostic, interviews Dr. Frank, Hstau, and Melissa. They explain how their goldfish concept relates to covariance analysis when dealing with heterogeneous samples in cryo-EM. Click here to read the Q&A.