News

Nobel Prize ceremony and more

Posted by: Joachim Frank  |  December 17, 2017  |  No comment
 

Click the links below to watch all of the Nobel programs.

  Nobel Prize Ceremony available until 8 June 2018 Thomas von Heijne program leader and guides us through the award ceremony in the Concert Hall.  
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2017 Nobel Prize in Chemistry

Posted by: Joachim Frank  |  October 4, 2017  |  Comment
Interview on Spiegel TV:

Just posted in BioRxiv

Posted by: Joachim Frank  |  July 26, 2017  |  No comment
"Conformational Dynamics and Energy Landscapes of Ligand Binding in RyR1" Ali Dashti, Danya Ben Hail, Ghoncheh Mashayekhi, Peter Schwander, Amedee des Georges, Joachim Frank, Abbas Ourmazd Click here to read. Biorxiv...

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New paper in Nature

Posted by: Joachim Frank  |  July 26, 2017  |  No comment
Channel opening and gating mechanism in AMPA-subtype glutamate receptors Edward C. Twomey, Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank &
Alexander I. Sobolevsky The paper is now out in accelerated format. Click here to read. See below for Columbia press release. http://newsroom.cumc.columbia.edu/blog/2017/07/24/scientists-capture-first-image-major-brain-receptor-action/

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Photos of the new Krios Titan microscope

Posted by: Joachim Frank  |  April 25, 2017  |  No comment

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Paper accepted by The Journal of Physical Chemistry

Posted by: Joachim Frank  |  February 15, 2017  |  No comment
Our paper describing work in collaboration with the late Klaus Schulten, “Quantitative Characterization of Domain Motions in Molecular Machines” by Suvrajit Maji, Rezvan Shahoei, Klaus Schulten and Joachim Frank, has just been accepted by  The Journal of Physical Chemistry Part B -- Biophysical Chemistry, Biomaterials, Liquids, and Soft Matter.  It will appear in a Special Issue dedicated to the memory of Klaus Schulten. Click here for full article. ABSTRACT The work of molecular machines such...

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Paper accepted by Structure

Posted by: Joachim Frank  |  February 6, 2017  |  No comment
An article describing the design and testing of a new PDMS-based micro-sprayer, in collaboration with the Columbia Engineering Department, has just been accepted by the journal STRUCTURE: A Fast and Effective Microfluidic Spraying-plunging Method for High-Resolution Single-Particle Cryo-EM Xiangsong Feng, Ziao Fu, Sandip Kaledhonkar, Yuan Jia, Binita Shah, Amy Jin, Zheng Liu, Ming Sun, Bo Chen, Robert A. Grassucci, Yukun Ren, Hongyuan Jiang, Joachim Frank, and Qiao Lin. Summary We describe a spraying-plunging method for preparing cryo-EM grids with vitreous ice of controllable, highly...

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Just accepted by EMBO Journal

Posted by: Joachim Frank  |  February 3, 2017  |  No comment
Title: Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis. Authors: Andrey G. Malyutin, Sharmishtha Musalgaonkar, Stephanie Patchett, Joachim Frank, and Arlen W. Johnson. Abstract: During ribosome biogenesis in eukaryotes, nascent subunits are exported to the cytoplasm in a functionally inactive state. 60S subunits are activated through a series of cytoplasmic maturation events. The last known events in the cytoplasm are the release of Tif6 by Efl1 and Sdo1 and the release of the export adapter, Nmd3, by the GTPase Lsg1. Here, we have used...

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Don Caspar’s 90th Birthday Symposium

Posted by: Joachim Frank  |  January 26, 2017  |  No comment
JANUARY 7-8, 2017 at Florida State University, Tallahassee “Don Caspar presenting Kepler’s solar system in Dürer’s pentagonally illuminated sanctum,” a montage by James Clarage. http://biophysics.fsu.edu/caspar-structural-biology-symposium/ I had the privilege of being invited to Don Caspar’s Symposium, which brought together many of his close associates,...

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Coming soon: Perspectives on the Ribosome

Posted by: Joachim Frank  |  January 23, 2017  |  No comment
The Royal Society will be publishing a special issue on January 30, 2017 featuring Perspectives on the Ribosome. Click here for a sneak peak.  

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