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Learning Materials
Meeting 1: FEG
Slides
180814_Meeting_1_FEG.180814.1255.pdf
Meeting 2: Magnetic Lenses
Slides
180828_Meeting_2_Magnetic_lenses.180828.1153.pdf
Meeting 3: Camera
Slides
180911_Meeting_3_Electron_detectors.180911.0847.pdf
Papers
2009-Detective_quantum_efficiency_of_electron_area_detectors_in_electron_microscopy.pdf
2009-Enhanced_imaging_in_low_dose_electron_microscopy_using_electron_counting..pdf
2014-Comparison_of_optimal_performance_at_300keV_of_three_direct_electron_detectors_for_use_in_low_dose_electron_microsc.pdf
Chapter_01_McMullan_2016_Methods-in-Enzymology.pdf
Meeting 4: CTF
Slides
190825_Meeting_4_CTF.180925.1009.pdf
Papers
1992-A_brief_look_at_imaging_and_contrast_transfer.pdf
1997-Three-Dimensional_Reconstruction_with_Contrast_Transfer_Function_Correction_from_Energy-Filtered_Cryoelectron_Micro.pdf
2015-CTFFIND4_Fast_and_accurate_defocus_estimation_from_electron_micrographs.pdf
2016-Gctf_Real-time_CTF_determination_and_correction.pdf
Erickson, Klug – 1971 – Measurement and compensation of defocusing and aberrations by Fourier processing of electron micrographs.pdf
Sigworth – 2016 – Principles of cryo-EM single-particle image processing.pdf
Zhang, Hong Zhou – 2011 – Limiting factors in atomic resolution cryo electron microscopy No simple tricks.pdf
Meeting 5: Specimen Support
Slides
191009_Meeting_5_Grids.181009.1249.pdf
Papers
Chapter_03_Passmore_2016_Methods-in-Enzymology.pdf
de_Jong_1992_Ultimate_resolution_and_informaton_in_EM_part-II.pdf
DImprima_2018_protein_denaturation_at_the_water-air_interface_and_how_to_prevent_it.pdf
elife-34257-v2.pdf
Glaeser-Han2017_Article_OpinionHazardsFacedByMacromole.pdf
McMullan_2015_Difussion_limit.pdf
Noble_et_al_2017_Routine_SP_cryoEM_sample_and_grid_characterization_by_tomography.pdf
Razinkov_2016-Nanowire_grids.pdf
Russo_Passmore_2014_Ultrastable.pdf
Russo_Passmore_2016_Progress_towards_an_optimal_specimen_support_for_electron_cryomicroscopy.pdf
Russo_Passmore_2016_Ultrastable.pdf
Van_Dyck_1992_Ultimate_resolution_and_information_in_EM.pdf
Meeting 6: Electron Specimen Interactions
Slides
191025_Meeting_6_Electron_specimen_interactions.181101.1410_redacted.pdf
Papers
2004-Radiation_damage_in_the_TEM_and_SEM.pdf
2008-Retrospective_radiation_damage_and_its_associated_information_limitations..pdf
2010-Origin_and_temperature_dependence_of_radiation_damage_in_biological_samples_at_cryogenic_temperatures..pdf
2013-Control_of_radiation_damage_in_the_TEM..pdf
Chapter_02_Glaeser_2016_Methods-in-Enzymology.pdf
Grant_Grigorieff_2015.pdf
TEM_Williams_Carter_2009_Ch_4.pdf
Meeting 7: Maximum Likelihood
Slides
Papers
2012-RELION_Implementation_of_a_Bayesian_approach_to_cryo-EM_structure_determination.pdf
Scheres_2016_MIE_v579.pdf
Sigworth_et_al_2010_MIE_v482.pdf